Thus, in the therapy of critical illness there is still ongoing research to optimize gastrointestinal microcirculation.
This probably increased gut permeability seems to play a role in the development of sepsis and multi-organ failure. Sepsis impairs gastrointestinal microcirculation and it is hypothesized that this might lead to mucosal barrier failure and subsequent translocation of bacteria and toxins into the bloodstream and local lymph system. The gastrointestinal microcirculation maintains, through sufficient oxygen and nutrient supply, an adequate mucosal cellular function.
0 kommentar(er)
